General Partners

Seth L. Harrison, MD, Managing General Partner
Seth Harrison has invested in life sciences since 1991. He has served as founding investor, acting CEO or chairman of numerous portfolio companies. Seth is currently Chairman and acting CEO of Tokai Pharmaceuticals and Chairman of Aileron Therapeutics. He is the managing general partner of Apple Tree Partners (ATP). Prior to founding ATP, Seth was a general partner at Oak Investment Partners and earlier had been a venture partner at Sevin Rosen Funds. His prior investments include: ArQule, Coelacanth, Cyrano Sciences, Gloucester Pharmaceuticals, Informed Access, SGX Pharmaceuticals, Ultracision and ViroPharma. Current portfolio investments include: Aileron Therapeutics, HeartWare International, and Tokai Pharmaceuticals. Seth received an A.B. from Princeton University, an MD and MBA both from Columbia University and completed a surgery internship at the Presbyterian Hospital. He serves on the board of the International Partnership for Microbicides, a Rockefeller Foundation/Gates Foundation sponsored public-private partnership engaged in the development of anti-HIV microbicides.